I’ve seen ads in the album art… That successfully gets carried over to the portable and displayed. But it’s not really interactive since it’s a static graphic rather than a clickable page.
Marc Cohen has a crusade on the topic of getting ads to work in the portable. Motto: “Don’t Sell The Music, Sell The Time Spent Listening To The Music.” I think that his POV is that there is no other place but the portable to sell the ad, since that’s where the listening hours are.